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      Piperazine anhydrous

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      Chinese alias Piperazine anhydrous; Diethylene diamine; 1,4-Diazacyclohexane; piperazinediium

      Colorless crystal with saline taste and ammonia odor.

      Structural formula
      CAS NO. 110-85-0
      EINECS 203-808-3
      Molecular formula
      Molecular Weight 86.14
      Melting point (℃) 109.6
      Boiling range 148.5

      Pharmaceutical intermediate, mainly used in the production of piperazine phosphate, piperazine citrate, bucinnazine, and rifampicin

      Physicochemical properties

      Saturated vapor pressure (kPa): 30.3/111℃
      Flash point (℃): 107(O.C)
      Solubility: Soluble in water, methyl alcohol, ethyl alcohol, slightly soluble in benzene and ethyl ether.
      Chemical properties: Combustion can give off toxic nitric oxide gas. Corrosive.


      Health hazard: Contact, inhalation or percutaneous absorption can cause weakness, blurred vision, ataxia, etc.

      First aid measures

      Skin contact: Take off the polluted clothing immediately, rinse with plenty of flow and clear water for at least 15 minutes, seek medical advice.
      Eye contact: Rinse with plenty of clear and<

      Fire-fighting measures

      Harmful combustion products: Carbon monoxide, carbon dioxide and nitric oxide.
      Fire extinguishing agent: spray water, foam, dry powder, carbon dioxide, sand.


      Emergency treatment: The contaminated areas should be isolated, cut off the source of ignition. The emergency treatment personnel shall wear dust mark, acid and alkali resistant clothes.

      Operation and storage

      Operation: The operator should be specially trained, follow the operating instruction. The operator should wear self-inhalation filter type dust respirator, chemical safety glasses, rubber acid and